hospital acquired infection Archives

Clostridium Difficile – Top Docs Radio

September 30, 2015 by angishields

Top Docs Radio

Clostridium Difficile - Top Docs Radio

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Clostridium Difficile

On this week’s episode we talked about one of the leading causes of hospital-acquired infections: Clostridium Difficile, or “C. Diff.” I sat down with Dr. David Dickensheets, infectious disease specialist with Infectious Disease Services of Georgia in his Cumming, GA office.

According to the CDC nearly half a million persons experienced a Clostridium difficile infection last year. Their website explains:

“Approximately 29,000 patients died within 30 days of the initial diagnosis of C. difficile. Of those, about 15,000 deaths were estimated to be directly attributable to C. difficileinfections, making C. difficile a very important cause of infectious disease death in the United States. More than 80 percent of the deaths associated with C. difficile occurred among Americans aged 65 years or older. C. difficile causes an inflammation of the colon and deadly diarrhea.

Previous studies indicate that C. difficile has become the most common microbial cause of healthcare-associated infections in U.S. hospitals and costs up to $4.8 billion each year in excess health care costs for acute care facilities alone. The new study found that 1 out of every 5 patients with a healthcare-associated C. difficile infection experienced a recurrence of the infection and 1 out of every 9 patients aged 65 or older with a healthcare-associated C. difficile infection died within 30 days of diagnosis.”

Clearly it’s a big problem. Dr. Dickensheets shared some great information on how the infection is diagnosed and why it’s so hard to eradicate from a hospital environment. He also talked about an interesting treatment approach–the fecal transplant.

That’s right, in some instances, patients have been able to resolve the infection by having fecal material from a healthy human instilled into their bowel, allowing a repopulation of normal flora bacteria that compete with the C. Diff., helping to eliminate the infection.

Special Guest:

Dr. David Dickensheets, MD, of Infectious Disease Services of Georgia

Doctor of Medicine, Thomas Jefferson University
Residency, Roger Williams Medical Center
Fellowshp, Brown University
Board Certified in Infectious Disease

Fighting Infections

July 6, 2015 by angishields

Health Connect South

Fighting Infections

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GeoVax — Debora Carrier, Michael Hellerstein, Jay Schafer

Fighting Infections

This week we hosted two experts whose companies are fighting infections from different directions. Michael Hellerstein is the Director of Regulatory Affairs and Quality Systems for GeoVax. They’re a biotechnology company that’s developing vaccines for Ebola and HIV.

Debora Carrier combined her experience as a fashion model and a healthcare provider to think of a better-looking scrub uniform that is both better looking and resistant to spreading infections. She founded Twice As Nice Uniforms to give health workers and physicians a more visually appealing choice while at the same time helping reduce the alarming rate of infections acquired in health delivery environments.

Michael talked about how GeoVax has been fighting infections through innovative approaches to vaccine development, utilizing vaccine-like particles to tackle HIV and more recently, Ebola. He shared how prevalent HIV remains today and that more work is being focused on treating the disease versus developing vaccines to prevent it.

He shared how technology has evolved that allows biotech companies to identify genetic components to viruses, which enables them to incorporate pieces of this material and instill it into a harmless organism. Then, as the organism reproduces, it produces a copy of itself that has some characteristics of the pathogen the vaccine is designed to fight. This “recombinant” vaccine doesn’t make the body sick but it does prompt an immune response from the body against the pathogenic virus, providing protection against infection.

GeoVax is able to create particles that are safer to use than vaccines that contain live pathogen, allowing people who may have some immune compromise to get some protection as well in some cases.

The company has used this technology to get a vaccine that is showing some promise for preventing HIV infection. Michael talked about how the clinical trials are progressing and how long it takes to get a vaccine approved for use in people versus the time it takes to develop a medication to treat disease.

Debora talked about her story as a healthcare provider for over 20 years led her to think of a scrub design that looks much better than the bulky, wrinkle-prone scrubs the health community has been using for decades. She talked about how frequently the environment is very cool, prompting workers to wear long sleeves and/or jackets while delivering care.

We discussed how long sleeves prevent washing the lower arms as is recommended and how the fabric can readily carry bacteria and viral material from one patient to another. Debora investigated various athletic materials that can help regulate body temperature in various climes, while at the same time possessing antimicrobial properties.

Twice As Nice Uniforms utilize an American-made material that controls moisture and uses a scrub design that incorporates a removable liner that allows the worker to be comfortable when the rooms are very cool.

In looking at the design of the garments, it’s clear she brought her experience in modeling to bear in the style/cut of the uniforms they’re creating.

Special Guests:

Debora Carrier, CEO/Founder of Twice As Nice Uniforms

AS, Dental Hygiene, William Rainey Harper College
Professional Fashion Model
Registered Dental Hygienist
Founder, CPR Sisters

Michael Hellerstein, Director of Regulatory Affairs and Quality Systems

AB, Biology, Harvard University
Previous Assistant Scientist, Pfizer
Co-Founder, BlueSky Biotech
President, Hellerstein Consulting

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Hospital Acquired Conditions

May 22, 2015 by angishields

Health Connect South

Hospital Acquired Conditions

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Hospital Acquired Conditions

According to CDC, there were over 700,000 hospital acquired conditions in 2011 (in this case, infections). When you add those numbers to other preventable situations such as falls, wrong drug/dose/patient, and others, it’s clear that hospitals can be potentially-dangerous places. This week, Diana and I sat down with two experts from companies that are tackling this problem from different directions.

HanGenix, an Atlanta-based start-up is developing an innovative technology that employs ultrasound transmitters/receivers on soap dispensers, on the clinicians’ badges, and in the patients’ rooms with the goal of increasing compliance with hand-washing standards. CEO, Jeff Kline, talked about how each patient bed is “guarded” by an ultrasonic receiver that communicates with the clinician’s badge and soap dispenser in the room or nearby.

The system starts a clock that will alert the health worker that they need to re-wash their hands if too much time elapses between washing their hands and touching the patient. The bed’s zone receiver also prompts an audible alert on the worker’s badge if they approach the patient’s bed without having registered a hand-washing event detected by the system.

Early returns from health systems that are participating in the testing of the prototype have shown that hand washing compliance is as low as 40% before implementing the technology and rises rapidly once it is deployed. This is significant, as hand-washing has been identified as one of the most effective means to prevent spread of infections from patient-to-patient in a healthcare environment.

Synensis’s Chief Innovation Officer, Rick Stone, joined the conversation to talk about how their company works with their healthcare clients to assess the organization’s internal culture relating to behaviors that reduce hospital acquired conditions such as falls, infections, and other sentinel events. Through an in-depth assessment at the outset of their engagement, Synensis’s team formulates a picture of how an organization prioritizes policies/procedures that can reduce/prevent those sentinel events.

The company then begins to interface with all levels of leadership and front-line providers to raise awareness and put in place actions such as debriefings after untoward events occur so that better team work can result. Synensis also helps hospitals identify areas of their organization that have particularly low rates of sentinel events to draw from their localized culture/approach to prevention to the betterment of the organization as a whole. As Rick stated, “Hospitals have teams of experts. But, few have expert teams,” pointing out that in many industries, healthcare included, poor communication and/or teamwork is the primary culprit in accidents.

Special Guests:

Jeff Kline, CEO/Co-founder, HanGenix